Q03327

Name	Mitochondrial fusion and transport protein UGO1
Uniprot ID	Q03327
Systematic gene name	YDR470C
Standard gene name	UGO1
Gene names	UGO1 YDR470C
Description from SGD	YDR470C UGO1 SGDID:S000002878, Chr IV from 1401214-1399706, Genome Release 64-3-1, reverse complement, Verified ORF, "Outer membrane component of the mitochondrial fusion machinery; binds to Fzo1p and Mgm1p to link these two GTPases during mitochondrial fusion; involved in fusion of both the outer and inner membranes; facilitates dimerization of Fzo1p during fusion; import into the outer membrane is mediated by Tom70p and Mim1p; has similarity to carrier proteins but likely not a transporter; similar to human SLC25A46 implicated in optic atroprophy spectrum disorder and Leigh syndrome"
Protein length	502
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

MNNNNVTEAT SRAQIRPYYD PDSFNAGYSA VFKPDEGVVD PHGYTIASKL
NVINSSPTTK RMANALFKSS PMKKLSNSVN DGLSLEGSNG EITGLNNFEW
AELVNIQKWR KIFEQLLDMF FRKYFQLLIQ QPFDVARLLI QVGEFKIFKT
TVDTNKPQAP IILRDEEGDG AAREGEEDAY DEEEIDFFPI ERKIAEANST
APIMAEETDH SHHEPTDISL TIAPQSLHTI DVINALFDQE GIRGLWKANN
TTFIYNFLSL SIDTWFTGLL SSFLGVPDPY FMEVINSPDI SKSFILALGA
GVFTSIILLP VDLIRTRLIV TSFKKKKNVK TDGKNMVTNT RSLRQLIRCW
SWRKNGVSIP LDMWSLTILQ SINNSFFNKL FDLVIYNQFH IEKYSQTVMY
NTMKFFSKSL ELFIKLPLEN LLRRCQLNYL LNDQRLSFKV DSTELIVKPK
KYNGIWDVIR NNSNTNRGQL WNGWKVGVIS LICGYGLQMM NKVDINMEQE
KF

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[55, Phos]	Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications)
[56, Phos]	Guo X, Niemi NM, Coon JJ, Pagliarini DJ (2017a) Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase. J Biol Chem 292:11751–11759. (Publication) (All modifications)
[56, Phos]	Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications)
[56, Phos]	Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[56, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)