Basic Information

NamePutative esterase YMR210W (EC 3.1.1.-)
Uniprot IDQ03649
Systematic gene nameYMR210W
Standard gene nameMGL2
Gene namesMGL2 YMR210W YM8261.04
Description from SGDYMR210W MGL2 SGDID:S000004823, Chr XIII from 687516-688865, Genome Release 64-3-1, Verified ORF, "Monoacylglycerol and triacylglycerol lipase; MAG lipase with preference for palmitoyl-MAG; TAG lipase involved in TAG catabolism; minor role in medium-chain fatty acid ethyl ester biosynthesis; contains an alpha/beta hydrolase domain and a typical lipase motif (GXSXG); similar to acyltransferases, Eeb1p, Eht1p, and human ABHD1"
Protein length449
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MRLKELLPNF LIVHQEVPED PIAFKSTDKR ENENKEITIP ELIDTKVPEL
ADGATDTLYG LLVNGHLQTA YGSFRHFDNI YKVQYKRMII KYPHGGEGTV
DFAVNGRSTK RRKVEKEYVP TSQPVFNGNL KRRYSYYSPD DPKLNSDDAK
PMLIILHGLT GGSRESYVRA IVHEITTKYD FEACVFNARG CCYSAITTPL
LYNGGWTNDI RYCVNDLRKR FPNRKFYMMG FSLGASIMTN YLGEESDRTK
IECAISVSNP FDLYNSAYFI NSTPMGSRFY SPALGHNLLR MVRNHLSTLE
ENPDFKDVIE KHLKKIRTVR QFDNLLTGPM FGYKNAEEYY KNASSYKRIP
GIRTPFIALH AQDDPIVGGD LPIDQIKSNP YTLLLETSTG GHVGWFKDRS
GRRWYAEPLC RFLKIFHDEI TVKGLKPDLE NVQLPDPNCE PIATTFRAN

Legend

  • X Ubiquitination
  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[82, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[131, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[135, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[135, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[135, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[138, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)