Basic Information
Name | Dephospho-CoA kinase CAB5 (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) |
Uniprot ID | Q03941 |
Systematic gene name | YDR196C |
Standard gene name | CAB5 |
Gene names | CAB5 YDR196C YD9346.07C |
Description from SGD | YDR196C CAB5 SGDID:S000002604, Chr IV from 850999-850274, Genome Release 64-3-1, reverse complement, Verified ORF, "Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; involved in histone acylation; null mutant lethality is complemented by human homolog DCAKD and by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies; also localized to lipid droplets" |
Protein length | 241 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MLVVGLTGGI ACGKSTVSRR LRDKYKLPIV DADKIARQVV EPGQNAYDQI
VLYFKDKIPN LLLEDGHLNR EALGKWVFSH KEDLQALNGI THPAIRYAMF
KEIGYYYLKG YRMCVLDVPL LFEGNLDSIC GVTVSVICTQ ELQLERLMTR
NPELSEEDAK NRLNSQMSTE ERMARSDYIL QNNSTLVDLY EQIESVVKKI
QPSKLRTVLE YFPPFGAVSA SSIVMSRLLM KKLQNKKSSA V
VLYFKDKIPN LLLEDGHLNR EALGKWVFSH KEDLQALNGI THPAIRYAMF
KEIGYYYLKG YRMCVLDVPL LFEGNLDSIC GVTVSVICTQ ELQLERLMTR
NPELSEEDAK NRLNSQMSTE ERMARSDYIL QNNSTLVDLY EQIESVVKKI
QPSKLRTVLE YFPPFGAVSA SSIVMSRLLM KKLQNKKSSA V
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[149, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[149, Phos] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[168, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[169, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |