Basic Information
| Name | Thiamine-repressible mitochondrial transport protein THI74 |
| Uniprot ID | Q04083 |
| Systematic gene name | YDR438W |
| Standard gene name | THI74 |
| Gene names | THI74 YDR438W |
| Description from SGD | YDR438W THI74 SGDID:S000002846, Chr IV from 1338274-1339386, Genome Release 64-3-1, Verified ORF, "Mitochondrial transporter repressible by thiamine; THI74 has a paralog, YML018C, that arose from the whole genome duplication; shows sequence homology to human gene SLC35F3, a thiamine transporter implicated in hypertension" |
| Protein length | 370 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MNRVGIDVDH MIGVLLLAVV VVFWVGASCL TNELLETNAY NKPFFLTYLN
ISSFALYLTP DLWRIIQSRR KSLQERTERT LPIHTQESFS EFLPLLSSTP
STSSNLSSIA DTKVKDTMRL SLLFCVLWFV ANLAANAALS YTTVASSTIL
SSTSSFFTLF LATSLGIETF STKKLLGLFV SLFGIILIVM QSSKQQDSVS
ASSFLVGNTL ALLGSLGYSV YTTLLKYEIS SKGLRLDIQM FLGYVGIFTF
LLFWPILIIL DITHMETFEL PSNFHISFLV MLNCIIIFVS DYFWCKALIL
TSPLVVTVAL TFTIPLAMFA DFVWREAFFT PWYIIGVIFI FVSFFLVNHR
GESAVEKDCA AVEKGPILDA
ISSFALYLTP DLWRIIQSRR KSLQERTERT LPIHTQESFS EFLPLLSSTP
STSSNLSSIA DTKVKDTMRL SLLFCVLWFV ANLAANAALS YTTVASSTIL
SSTSSFFTLF LATSLGIETF STKKLLGLFV SLFGIILIVM QSSKQQDSVS
ASSFLVGNTL ALLGSLGYSV YTTLLKYEIS SKGLRLDIQM FLGYVGIFTF
LLFWPILIIL DITHMETFEL PSNFHISFLV MLNCIIIFVS DYFWCKALIL
TSPLVVTVAL TFTIPLAMFA DFVWREAFFT PWYIIGVIFI FVSFFLVNHR
GESAVEKDCA AVEKGPILDA
Legend
- X Ubiquitination
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
| [364, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |