Basic Information

NameNuclear fusion protein KAR5 (Factor-induced gene 3 protein) (Karyogamy protein 5)
Uniprot IDQ04746
Systematic gene nameYMR065W
Standard gene nameKAR5
Gene namesKAR5 FIG3 YMR065W YM9916.04
Description from SGDYMR065W KAR5 SGDID:S000004669, Chr XIII from 399702-401216, Genome Release 64-3-1, Verified ORF, "Protein required for nuclear membrane fusion during karyogamy; localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; similar to zebrafish Brambleberry protein; expression of the gene is regulated by pheromone"
Protein length504
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MFEMRYVYLF AICIKFVSSS ELGKINNLLQ GRLIYTDNSV ATNVLESKFP
FLKSTCVKDA LKLFLPQCIA NGLESIDAET RVETAIKLSI CEFQASGLGE
IPENCMVDDL GSMMDCMFEL ESSSQWWTTY SGNYQRLSSI CYENLLPFEK
EQILKLFLNI TELYDSFGDD VDTKLNHLMF QMEQDSQNFL DDLARMFRNY
DNELRNATES NRIILENDLS FFRNKVNDVL YETSEQLEVQ IIEKNSQLMN
EVDTVHHIMS DLADELAKND IKSKINDLKD DSLNNLQDLV EMSNDVKEYY
SRNNKLVNTE LENFSMGLKK QLGGMSKDLS ESQMEAIELL QGFNSILHDS
LLPSMTDEIV PEMTNFKNTL LQEWTAITST LNGDFALWNE EIFSTFNDIS
EKLNGTKKKL DDIEIRVSLV HKNVMTMMRV LDFMWKTSKM IIRCGYLAVK
NKYYWLLCSV VWIWSKYRTS RVNVKMIPIK RYYQWAALLL SIYLGAKTGS
LIDF

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[18, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[18, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[20, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[20, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)