Basic Information

Name1,3-beta-glucan synthase component FKS3 (EC 2.4.1.34) (1,3-beta-D-glucan-UDP glucosyltransferase) (FK506 sensitivity protein 3)
Uniprot IDQ04952
Systematic gene nameYMR306W
Standard gene nameFKS3
Gene namesFKS3 YMR306W YM9952.08
Description from SGDYMR306W FKS3 SGDID:S000004923, Chr XIII from 881159-886516, Genome Release 64-3-1, Verified ORF, "Protein involved in spore wall assembly; has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"
Protein length1785
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MDFMSPKFSL TDVEYPAWCQ DDEVPITMQE IREIFVELMD KFGFQKSSME
NMYQHLMGQL DSRASRTGAQ NALVSLHVSY IGGEHANYRK WYFAAQLDLD
EEIGFQNMRL HGKARQRNVK MAKKRGVSIK EQIKQWNEKE QEFINNHPKI
TLTQEQLEDQ TNLKSADYKW KLKMKKLTPE NMIRQLALYL LCWGEANQVR
FAPECLCFIF KCALDYDIST SSSEKTVKSP EYSYLNDVIT PLYEFLRGQV
YKKDAKGNWK RREKDHKNII GYDDINQLFW YPEGFERIIL NNGERLVDKP
LEERYLYFKD VAWSKVFYKT YRETRSWKHC FTNFNRFWII HFAPFWFFTT
FNSPTLYTKN YIQLLNNQPT PQVRLSVIAF GGTIACLVQI LATVFEWGFV
PREWPGAQHL SSRMIGLLFC LAINLGPSVY VLGFFEWDVH SKSAYIVSIV
QLIIAFLTTF FFAVRPLGGL FRPYLNKDKK HRRYISSQTF TASFPKLTGR
SKWFSYGLWV FVYLAKYIES YFFLTLSLRD PIRVLSIMDL SRCQGEYLLG
PILCKWQAKI TLVLMLLSDL GLFFLDTYLW YIICNCIFSI VLSFSLGTSI
LTPWKNVYSR LPKRIYSKIL ATSEMDVKFK AKILISQVWN AIVISMYREH
LLSIEHLQRL LFQQVDSLMG DTRTLKSPTF FVAQDDSTFK SMEFFPSNSE
AKRRISFFAQ SLATPISEPV PVDCMPTFTV LVPHYSEKIL LGLKEIIREE
SPKSKITVLE YLKHLHPTEW ECFVKDTKLL SMEKSFLKEA ESSHDEDRLE
IPDALYDPRS SPLSDHTESR KLPTEDDLIK EKINDLPFSY FGFNSSEPSY
TLRTRIWASL RTQTLYRTLS GFMNYSKAIK LLYRIENPSL VSLYRGNNEA
LENDLENMAS RKFRMVVAMQ RYAKFNKDEV EATELLLRAY PNMFISYLLE
ELEQNESEKT YYSCLTNGYA EFDEESGLRK PIFKIRLSGN PILGDGKSDN
QNHSIIFYRG EYIQVIDANQ DNYLEECLKI RSVLSEFEEL ELNPTIPYIP
GIEYEEEPPP IAIVGSREYI FSENIGVLGD IAAGKEQTFG TLFARTLAEI
GGKLHYGHPD FLNGIFMTTR GGLSKAQRGL HLNEDIYAGM NAICRGGKIK
HSDYYQCGKG RDLGFGSILN FTTKIGAGMG EQLLSREYYY LGTQLPMDRF
LSFFYAHPGF HLNNLFISFS VQLFFVLLLN LGALNHEIIA CFYDKDAPIT
NLETPVGCYN IQPALHWVSI FVLSIFIVFF IAFAPLLIQE VLEKGIWRAA
SRFLHHLLSM APLFEVFVCQ VYSNSLLMDL TFGGAKYIST GRGFAITRLD
FFTLYSRFVN ISIYSGFQVF FMLLFAIISM WQPALLWFWI TVISMCFAPF
IFNPHQFAFM DFFIDYKTFI HWLFSGNTKY QKESWANFVK SSRSRFTGYK
SKTVDDISED SGHDSKKARF WNVFFAELFL PFCVFLFNFT AFSFINAQTG
VSDSTPTSAV FRLLLVTFLP IFLNSIVLFL LFWVSLFVVP GLSYCCKDAG
AVIAFIAHTF SVLVYLLDFE LMWFLQGWNF TRTLILLITC INMHLILFKV
FTTIFLTREY KNNKAHLAWW NGKWYNTGMG WSIILQPIRE YFVKIMESSY
FAADFFLGHF LLFIQTPIIL LPFIDYWHTM VLFWMNPRSI IAHKRILTRK
QRALRSRIVS KYFSLYFVML GVLLFMLIAP FFAGDFVSSP QELLEGTLFE
GIFQPNNQNN NDTGPNAPST ILTTTPTLPT FRTVA

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[506, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[513, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[595, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[667, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[672, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[1124, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[1124, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)