Basic Information

NameUncharacterized protein YLR283W, mitochondrial
Uniprot IDQ05867
Systematic gene nameYLR283W
Standard gene namePUT7
Gene namesPUT7 YLR283W
Description from SGDYLR283W PUT7 SGDID:S000004273, Chr XII from 705186-706130, Genome Release 64-3-1, Uncharacterized ORF, "Regulator of mitochondrial proline metabolism; tethered with Fmp32p to inner mitochondrial membrane in large hetero-oligomeric complex, abundance of which is regulated by proline; involved in mitochondrial proline homeostasis and cellular redox balance; null exhibits pronounced defect in proline utilization, and can be functionally complemented by expression of human homolog MCUR1"
Protein length314
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MMRLIRTLPL RCFKTRIRRQ GSLLCLRCFS SYSKPLLQKS MSLKNIQLSD
LSSSPLSKNK EKQEKPEKEN EGKHSIGLLD RFSEDFITQG NGLKPTTSQN
QLDTIKFYQM LRERGNFSDE QCKIIIALLL QLLNDQFYSC YNDLFLRDME
LNKQSHLFSS LETELKFAIQ NSRDTQLNEH HLQLLKLKRE LNSIHDELNE
IIIDLLQKDA KLEFNNQKLE NTLLYRQLNL KLNDCSNKIQ TKILGDIRSH
IENLRWQTTR SGLLVILVLV CSIMIGVSAS KKERPGLQEP EEPEILAPKE
DIDTTFPQDQ HDID

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[278, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[278, Phos]Holt, L.J.,  Tuch, B.B.,  Villén, J.,  Johnson, A.D.,  Gygi, S.P.,  Morgan, D.O. (2009). Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948): 1682-1686. (Publication) (All modifications)
[278, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)