Basic Information

NameUncharacterized oxidoreductase TDA5 (EC 1.-.-.-) (Topoisomerase I damage affected protein 5)
Uniprot IDQ06417
Systematic gene nameYLR426W
Standard gene nameTDA5
Gene namesTDA5 YLR426W
Description from SGDYLR426W TDA5 SGDID:S000004418, Chr XII from 987062-987141,987213-988113, Genome Release 64-3-1, Uncharacterized ORF, "Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele"
Protein length326
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MNIDCLCRWV VLPLLRYPLL VALVLRWSLS DSISICLTIY TLLINAFLIA
NSYIKRSGQV AWKSLREFKN GIVLITGGSK GLGRAIVSQL LQDYSNLTIL
NVDICPSSVR NTRVKDLICD LSDDEEVAAL LNLLKRKYKN EIRLIVNNAG
VRANFTGFNG MERDNLDKIF KINTFAPLQF IQELAPSRHS TRQCYIVNIA
SILGILTPAK VAAYAASKAA LIAFHQSYSF ELQNEGVRNI RTLLVTPGQL
NTEMFAGFKP PRQFFAPVID ITTLAAKIVR YCELGQRGQL NEPFYCSFAH
LLMCVPYSLQ RIVRSFSRID CCLPDE

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[187, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[272, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[273, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)