Basic Information
Name | LETM1 domain-containing protein YLH47, mitochondrial (LETM1 homolog) |
Uniprot ID | Q06493 |
Systematic gene name | YPR125W |
Standard gene name | YLH47 |
Gene names | YLH47 MRS7 YPR125W |
Description from SGD | YPR125W YLH47 SGDID:S000006329, Chr XVI from 787961-789325, Genome Release 64-3-1, Verified ORF, "Mitochondrial inner membrane protein; exposed to the mitochondrial matrix; associates with mitochondrial ribosomes; NOT required for respiratory growth; homolog of human Letm1, a protein implicated in Wolf-Hirschhorn syndrome" |
Protein length | 454 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MLKYRSLPIK RAIHHPAPGI TPISPRIMVS RLRVIPSFNL KFNRWNSSVP
ESSKKELKTT DGNQESASKV SPVKEKEKVP FKVKMQKALR HYWDGSKLLG
LEIKISSKLL MKSAAGYPLT RRENLQLKRT TQDIVRLVPF AAFLIIPFAE
LLLPFALKLF PNLLPSTYES SKKRENKLEN LRNTRKLMSE IIKNNKSHFK
PNNISEEQKA LFNRFYTHVR ATGVPESRQQ LIEVARLFTD DTVLDNVTRP
YLIALAKYMN LQPFGTDVML RYRIRYKMLE LKKDDLSIYY EDAEQLSLSE
LKTACASRGI RSVDVEPSVL YSNLRLWLNM RLKDKIPSTL LIMATAYNYG
NVQSKESLYD ALCDVLIGIP DELYHEVKVN VVKEDEASAK QKLKQLREQE
EIMKEEEQQE ENAIVSVKDE LSLDDQDKNI DAAAPDVKPH DTKPIGEAAA
IKEK
ESSKKELKTT DGNQESASKV SPVKEKEKVP FKVKMQKALR HYWDGSKLLG
LEIKISSKLL MKSAAGYPLT RRENLQLKRT TQDIVRLVPF AAFLIIPFAE
LLLPFALKLF PNLLPSTYES SKKRENKLEN LRNTRKLMSE IIKNNKSHFK
PNNISEEQKA LFNRFYTHVR ATGVPESRQQ LIEVARLFTD DTVLDNVTRP
YLIALAKYMN LQPFGTDVML RYRIRYKMLE LKKDDLSIYY EDAEQLSLSE
LKTACASRGI RSVDVEPSVL YSNLRLWLNM RLKDKIPSTL LIMATAYNYG
NVQSKESLYD ALCDVLIGIP DELYHEVKVN VVKEDEASAK QKLKQLREQE
EIMKEEEQQE ENAIVSVKDE LSLDDQDKNI DAAAPDVKPH DTKPIGEAAA
IKEK
Legend
- X Phoshorylation
- X K-acetylation
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
Use imported representation
Loading structure from server... It may take a while.
If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.
- Internet Explorer: sorry. IE doesn't support WebGL.
- Firefox (version 4 or later): try force enable WebGL.
- Chrome: try force enable WebGL.
- Safari: enable WebGL.
References
[71, Phos] | Renvoisé M, Bonhomme L, Davanture M, et al (2014) Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. Journal of Proteomics 106:140–150. (Publication) (All modifications) |
[71, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[200, K-acetyl] | Henriksen, P., Wagner, S. A., Weinert, B. T., et al. (2012). Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Molecular & Cellular Proteomics, 11(11), 1510-1522. (Publication) (All modifications) |
[383, K-succ] | Weinert, B.T., Schölz, C., Wagner, S.A., et al. (2013). Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Reports, 4(4), 842-851. (Publication) (All modifications) |
[383, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[388, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[390, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |