Basic Information

NameProtein SYM1 (Stress-inducible yeast MPV17 protein 1)
Uniprot IDQ06563
Systematic gene nameYLR251W
Standard gene nameSYM1
Gene namesSYM1 YLR251W
Description from SGDYLR251W SYM1 SGDID:S000004241, Chr XII from 641464-642057, Genome Release 64-3-1, Verified ORF, "Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17; human homolog MPV17 is implicated in hepatocerebral mtDNA depletion syndromes (MDDS), and complements yeast null mutant"
Protein length197
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MKLLHLYEAS LKRRPKTTNA IMTGALFGIG DVSAQLLFPT SKVNKGYDYK
RTARAVIYGS LIFSFIGDKW YKILNNKIYM RNRPQYHWSN MVLRVAVDQL
AFAPLGLPFY FTCMSIMEGR SFDVAKLKIK EQWWPTLLTN WAVWPLFQAI
NFSVVPLQHR LLAVNVVAIF WNTYLSYKNS KVMEKDKVPV HYPPVVE

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[7, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[7, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)