Basic Information
Name | Putative ATP-dependent helicase IRC3 (EC 3.6.4.-) (Increased recombination centers protein 3) |
Uniprot ID | Q06683 |
Systematic gene name | YDR332W |
Standard gene name | IRC3 |
Gene names | IRC3 YDR332W |
Description from SGD | YDR332W IRC3 SGDID:S000002740, Chr IV from 1131001-1133070, Genome Release 64-3-1, Verified ORF, "Double-stranded DNA-dependent helicase of the DExH/D-box family; branch point-binding helicase that preferentially unwinds the nascent lagging strand with a 3' to 5' polarity at a replication fork; contains double-stranded DNA translocase activity; responsible for DNA branch migration; required for maintenance of the mitochondrial (mt) genome; localizes to the mitochondrial matrix; monomeric" |
Protein length | 689 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MTSTLATRLS TYSISLILQR IKIIKRCYSA PVLRDYQQDA IDACVNSIRQ
GTKRIGVSLA TGGGKTVIFS NLINQLRQNY FKERQGNFKS LILVHRRELA
LQATATLKKI FPDLKVHIEM GKYDCDIEDS DVIVASVQTL IRRLHKYDTN
SVNLIIIDEA HHSVANSYRS ILDHFKASTA ETKIPVIGFS ATFERADKRA
LSMVMDKIVY HRGILEMIDD KWLCEAKFTS VKIEADLSDV KSTADDFQLA
PLSSLMNTKE INEVILKTYL HKKQEKSLKS TLLFGVDKAH VQSLHKLFKD
NGINTDYVTS DTKQIERDNI IQKFKNGETE VLMNCGIFTE GTDMPNIDCI
LLCRPTKSRS LLIQMIGRGL RLHHSKDHCH IIDFIGASSV GVVSAPTLLG
IRSDDIEFDD ATVEDLKAIQ GEIIAKQQKI DERLRALFQT DEAAMENVTE
RNSVADWIHS ANSVDLTLCS FDSFRNFTQS NNSYPSGKEF DEASEAVKEM
ELLMNSQYPW VKFASNAWGL PLKGKNHLRI YKEKSEDKLS MVYHLKMYRQ
LPCFITNKYA DYVPKSIIKD ANLWNVMSKV EKIINTLNSD LEGQTMQYQA
ISSKYSKWRQ TVPTSKQRDF VFRKLKKVYG ESSKDFIRLS LDDVTTYVNT
KMTKGDASNL IFASSLAPVY PLKSLLRILE YQKRRSFIK
GTKRIGVSLA TGGGKTVIFS NLINQLRQNY FKERQGNFKS LILVHRRELA
LQATATLKKI FPDLKVHIEM GKYDCDIEDS DVIVASVQTL IRRLHKYDTN
SVNLIIIDEA HHSVANSYRS ILDHFKASTA ETKIPVIGFS ATFERADKRA
LSMVMDKIVY HRGILEMIDD KWLCEAKFTS VKIEADLSDV KSTADDFQLA
PLSSLMNTKE INEVILKTYL HKKQEKSLKS TLLFGVDKAH VQSLHKLFKD
NGINTDYVTS DTKQIERDNI IQKFKNGETE VLMNCGIFTE GTDMPNIDCI
LLCRPTKSRS LLIQMIGRGL RLHHSKDHCH IIDFIGASSV GVVSAPTLLG
IRSDDIEFDD ATVEDLKAIQ GEIIAKQQKI DERLRALFQT DEAAMENVTE
RNSVADWIHS ANSVDLTLCS FDSFRNFTQS NNSYPSGKEF DEASEAVKEM
ELLMNSQYPW VKFASNAWGL PLKGKNHLRI YKEKSEDKLS MVYHLKMYRQ
LPCFITNKYA DYVPKSIIKD ANLWNVMSKV EKIINTLNSD LEGQTMQYQA
ISSKYSKWRQ TVPTSKQRDF VFRKLKKVYG ESSKDFIRLS LDDVTTYVNT
KMTKGDASNL IFASSLAPVY PLKSLLRILE YQKRRSFIK
Legend
- X Phoshorylation
- X SUMOylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[535, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[535, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[543, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[543, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[569, SUMO] | Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications) |
[578, Phos] | Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications) |
[579, SUMO] | Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications) |
[582, SUMO] | Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications) |
[633, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[633, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |