Basic Information

NamePutative ATP-dependent helicase IRC3 (EC 3.6.4.-) (Increased recombination centers protein 3)
Uniprot IDQ06683
Systematic gene nameYDR332W
Standard gene nameIRC3
Gene namesIRC3 YDR332W
Description from SGDYDR332W IRC3 SGDID:S000002740, Chr IV from 1131001-1133070, Genome Release 64-3-1, Verified ORF, "Double-stranded DNA-dependent helicase of the DExH/D-box family; branch point-binding helicase that preferentially unwinds the nascent lagging strand with a 3' to 5' polarity at a replication fork; contains double-stranded DNA translocase activity; responsible for DNA branch migration; required for maintenance of the mitochondrial (mt) genome; localizes to the mitochondrial matrix; monomeric"
Protein length689
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MTSTLATRLS TYSISLILQR IKIIKRCYSA PVLRDYQQDA IDACVNSIRQ
GTKRIGVSLA TGGGKTVIFS NLINQLRQNY FKERQGNFKS LILVHRRELA
LQATATLKKI FPDLKVHIEM GKYDCDIEDS DVIVASVQTL IRRLHKYDTN
SVNLIIIDEA HHSVANSYRS ILDHFKASTA ETKIPVIGFS ATFERADKRA
LSMVMDKIVY HRGILEMIDD KWLCEAKFTS VKIEADLSDV KSTADDFQLA
PLSSLMNTKE INEVILKTYL HKKQEKSLKS TLLFGVDKAH VQSLHKLFKD
NGINTDYVTS DTKQIERDNI IQKFKNGETE VLMNCGIFTE GTDMPNIDCI
LLCRPTKSRS LLIQMIGRGL RLHHSKDHCH IIDFIGASSV GVVSAPTLLG
IRSDDIEFDD ATVEDLKAIQ GEIIAKQQKI DERLRALFQT DEAAMENVTE
RNSVADWIHS ANSVDLTLCS FDSFRNFTQS NNSYPSGKEF DEASEAVKEM
ELLMNSQYPW VKFASNAWGL PLKGKNHLRI YKEKSEDKLS MVYHLKMYRQ
LPCFITNKYA DYVPKSIIKD ANLWNVMSKV EKIINTLNSD LEGQTMQYQA
ISSKYSKWRQ TVPTSKQRDF VFRKLKKVYG ESSKDFIRLS LDDVTTYVNT
KMTKGDASNL IFASSLAPVY PLKSLLRILE YQKRRSFIK

Legend

  • X Phoshorylation
  • X SUMOylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


Use imported representation

Loading structure from server... It may take a while.

If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.

References

[535, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[535, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[543, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[543, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[569, SUMO]Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[578, Phos]Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[579, SUMO]Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[582, SUMO]Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[633, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[633, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)