Basic Information
Name | Mitochondrial glycine transporter (Heme biosynthesis protein of SLC25 family) (Solute carrier family 25 member 38 homolog) |
Uniprot ID | Q07534 |
Systematic gene name | YDL119C |
Standard gene name | HEM25 |
Gene names | HEM25 YDL119C |
Description from SGD | YDL119C HEM25 SGDID:S000002277, Chr IV from 247612-246689, Genome Release 64-3-1, reverse complement, Verified ORF, "Mitochondrial glycine transporter; required for the transport of glycine into mitochondria for initiation of heme biosynthesis, with YMC1 acting as a secondary transporter; homolog of human SLC25A38, a mitochondrial glycine transporter associated with nonsyndromic autosomal recessive congenital sideroblastic anemia; human SLC25A38 can complement the heme deficiency associated with the null mutant; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
Protein length | 307 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MTEQATKPRN SSHLIGGFFG GLTSAVALQP LDLLKTRIQQ DKKATLWKNL
KEIDSPLQLW RGTLPSALRT SIGSALYLSC LNLMRSSLAK RRNAVPSLTN
DSNIVYNKSS SLPRLTMYEN LLTGAFARGL VGYITMPITV IKVRYESTLY
NYSSLKEAIT HIYTKEGLFG FFRGFGATCL RDAPYAGLYV LLYEKSKQLL
PMVLPSRFIH YNPEGGFTTY TSTTVNTTSA VLSASLATTV TAPFDTIKTR
MQLEPSKFTN SFNTFTSIVK NENVLKLFSG LSMRLARKAF SAGIAWGIYE
ELVKRFM
KEIDSPLQLW RGTLPSALRT SIGSALYLSC LNLMRSSLAK RRNAVPSLTN
DSNIVYNKSS SLPRLTMYEN LLTGAFARGL VGYITMPITV IKVRYESTLY
NYSSLKEAIT HIYTKEGLFG FFRGFGATCL RDAPYAGLYV LLYEKSKQLL
PMVLPSRFIH YNPEGGFTTY TSTTVNTTSA VLSASLATTV TAPFDTIKTR
MQLEPSKFTN SFNTFTSIVK NENVLKLFSG LSMRLARKAF SAGIAWGIYE
ELVKRFM
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
Use imported representation
Loading structure from server... It may take a while.
If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.
- Internet Explorer: sorry. IE doesn't support WebGL.
- Firefox (version 4 or later): try force enable WebGL.
- Chrome: try force enable WebGL.
- Safari: enable WebGL.
References
[133, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[133, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[135, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[135, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[135, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[139, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[139, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[139, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[196, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[196, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[206, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[206, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |