Q07788

Name	Protein COS7
Uniprot ID	Q07788
Systematic gene name	YDL248W
Standard gene name	COS7
Gene names	COS7 YDL248W
Description from SGD	YDL248W COS7 SGDID:S000002407, Chr IV from 1802-2953, Genome Release 64-3-1, Verified ORF, "Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"
Protein length	383
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

MKENEVKDEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR
IWMLLWLPLS VWWKLSNNCI YPLIVSLLVL FLGPIFVLVI CGLSRKRSLS
KQLIQFCKEI TENTPSSDPH DWEVVVANLN SYLYENKAWN TKNFFFNATD
CEKMFRTTVL EPFSLKKDKA AKVKSFKDSV PYIEEALQVY ATGFDKQWKL
FITEKSWSPV GLEDVQLPKD IHRSKLTWFL KRIFTIYSLP LWLAFLNCIC
VSQHFCLAFR ILCPGLFFLM MVWLFQNMRT TALLVKMEHK MQFLLTIINE
QESGANGWDE IARKMNRYLF EKKAWKNEEF FFDGIDCEWF FSHFFYRLLS
AKKSMWLLPL NVELWPYIKE AQLSRNEESL MKK

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[10, Ubi]	Back, S., Gorman, A.W., Vogel, C., Silva, G.M. (2019). Site-specific K63 ubiquitinomics provides insights into translation regulation under stress. Journal of Proteome Research 18(1): 309-318. (Publication) (All modifications)
[18, Ubi]	Back, S., Gorman, A.W., Vogel, C., Silva, G.M. (2019). Site-specific K63 ubiquitinomics provides insights into translation regulation under stress. Journal of Proteome Research 18(1): 309-318. (Publication) (All modifications)
[382, Ubi]	Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)