Basic Information

NameProbable oxidoreductase ENV9 (EC 1.1.1.-) (Late endosome and vacuole interface protein 9)
Uniprot IDQ08651
Systematic gene nameYOR246C
Standard gene nameENV9
Gene namesENV9 YOR246C
Description from SGDYOR246C ENV9 SGDID:S000005772, Chr XV from 796793-795801, Genome Release 64-3-1, reverse complement, Verified ORF, "Conserved oxidoreductase involved in lipid droplet morphology; mutant shows defects in CPY processing and vacuolar morphology; required for replication of Brome mosaic virus in S. cerevisiae, a model system for studying replication of positive-strand RNA viruses in their natural hosts; homologus to human RDH12 linked to Leber Congenital Amaurosis"
Protein length330
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MLDPRILPYY DPAVERKIAV VTGGNTGIGW YTVLHLYLHG FVVYICGRNS
HKISKAIQEI LAEAKKRCHE DDDGSSPGAG PGPSIQRLGS LHYIHLDLTD
LKCVERAALK ILKLEDHIDV LVNNAGIMAV PLEMTKDGFE VQLQTNYISH
FIFTMRLLPL LRHCRGRIIS LSSIGHHLEF MYWKLSKTWD YKPNMLFTWF
RYAMSKTALI QCTKMLAIKY PDVLCLSVHP GLVMNTNLFS YWTRLPIVGI
FFWLLFQVVG FFFGVSNEQG SLASLKCALD PNLSVEKDNG KYFTTGGKES
KSSYVSNNVD EAASTWIWTV HQLRDRGFDI

Legend

  • X Ubiquitination

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[52, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[287, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)