Q12204

Name	Probable phospholipase YOR022C, mitochondrial (EC 3.1.1.-)
Uniprot ID	Q12204
Systematic gene name	YOR022C
Standard gene name	DDL1
Gene names	DDL1 YOR022C OR26.12
Description from SGD	YOR022C DDL1 SGDID:S000005548, Chr XV from 375857-373710, Genome Release 64-3-1, reverse complement, Verified ORF, "DDHD domain-containing phospholipase A1; mitochondrial matrix enzyme with sn-1-specific activity, hydrolyzing cardiolipin, PE, PC, PG and PA; implicated in remodeling of mitochondrial phospholipids; antagonistically regulated by Aft1p and Aft2p; in humans, mutations in DDHD1 and DDHD2 genes cause specific types of hereditary spastic paraplegia, while DDL1-defective yeast share similar phenotypes such as mitochondrial dysfunction and defects in lipid metabolism"
Protein length	715
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

MLRFTHRGLP SSTRFRNIFV RLNHIYVPWF YAIDVPNSKP YLPTYQTLHS
PKKFKPFSVD DSNRLEKASK RQERRPVLVN EDYLFKVDLS HMELSPTYWE
GPTYQVRRGV WFDSSNQPLS SDLTSEIEGL YKQLKFDDSN DDPTTTPPAE
SQDIFRLKGK YPVDKENEGE QKNGSSNKDE NESTFKFILF ANKQTAFLLS
DLDGGKLQLA FLRSNLAQSL PINATMITRS YKYSSSATTK QTSTSFKAAK
TPQTEVADGS NSSKSRSIET KLEKKVSNLF NLSDFLQLFN GNASKDQDDA
QSLEKQMETD YNNADNSQGA NASSKIEDGK NSGASDRQIR SNRRDVDNLI
LCVHGIGQTL GKKYEYVNFA HTVNLLRSNM KKIYNNSEKL QSLNTAPDYK
SNCNVQVLPI TWRHSISFQT DAKEENIENP DLPTLSQVTV NGVLPLRKLL
ADGLLDILLY VEPYYQDMIL QQVTSQLNKT YRIFKEFNPE FDGKVHLVGH
SLGSMILFDI LSKQKKYELE FQVDNLFFIG SPIGLLKLIQ RTKIGDRPEF
PNDLERKLTV QRPQCKDIYN VYHVCDPISY RMEPLVSKEM AHYEQTYLPH
CSEAYGLTSK VLEFGENIWK DLPGTDENNL QSKKTSPEKK EVKLSENLTR
MLTGLNYTGR LDYAMSPSLL EVDFISAIKS HVSYFEEPDI AAFILKEILS
KHENASEIYV KRKTG

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[243, Phos]	Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[243, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[244, Phos]	Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[244, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[245, Phos]	Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[245, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)