Basic Information
Name | Peroxisomal coenzyme A diphosphatase 1, peroxisomal (EC 3.6.1.55) |
Uniprot ID | Q12524 |
Systematic gene name | YLR151C |
Standard gene name | PCD1 |
Gene names | PCD1 YLR151C L9634.8 |
Description from SGD | YLR151C PCD1 SGDID:S000004141, Chr XII from 442737-441715, Genome Release 64-3-1, reverse complement, Verified ORF, "8-oxo-dGTP diphosphatase; prevents spontaneous mutagenesis via sanitization of oxidized purine nucleoside triphosphates; can also act as peroxisomal pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids; nudix hydrolase family member; similar E. coli MutT and human, rat and mouse MTH1" |
Protein length | 340 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MILSQRRMLS SKQLIENLIR YKFHKTPYTR SSIWPFKRNS AVIILLFIGM
KGELRVLLTK RSRTLRSFSG DVSFPGGKAD YFQETFESVA RREAEEEIGL
PHDPEVLHKE FGMKLDNLVM DMPCYLSRTF LSVKPMVCFL YKDKLEKHED
KYKVPLDIRK FFGKLNPGET SSLFSVPLND LVIHLLPEAD EDVKSYQAEY
FERKEYKLNW GGIKWLIMHY HFHVANNNEM PWLQTIEDLS SSDEDGVDGG
IFRFRDLWGL TCKILFDVSC IANGLMDEKL KGELGHEDLI VGLHDYGNQM
QPNGRSEWEI GMINGDRNLK YSDVIPEYYM KHLLECRSLW
KGELRVLLTK RSRTLRSFSG DVSFPGGKAD YFQETFESVA RREAEEEIGL
PHDPEVLHKE FGMKLDNLVM DMPCYLSRTF LSVKPMVCFL YKDKLEKHED
KYKVPLDIRK FFGKLNPGET SSLFSVPLND LVIHLLPEAD EDVKSYQAEY
FERKEYKLNW GGIKWLIMHY HFHVANNNEM PWLQTIEDLS SSDEDGVDGG
IFRFRDLWGL TCKILFDVSC IANGLMDEKL KGELGHEDLI VGLHDYGNQM
QPNGRSEWEI GMINGDRNLK YSDVIPEYYM KHLLECRSLW
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[69, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[69, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[69, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[241, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |