Basic Information
Name | Mitochondrial distribution and morphology protein 12 (Mitochondrial inheritance component MDM12) |
Uniprot ID | Q92328 |
Systematic gene name | YOL009C |
Standard gene name | MDM12 |
Gene names | MDM12 YOL009C |
Description from SGD | YOL009C MDM12 SGDID:S000005369, Chr XV from 310139-309324, Genome Release 64-3-1, reverse complement, Verified ORF, "Mitochondrial outer membrane protein, ERMES complex subunit; required for transmission of mitochondria to daughter cells; required for mitophagy; may influence import and assembly of outer membrane beta-barrel proteins; ERMES complex is often co-localized with peroxisomes and with concentrated areas of pyruvate dehydrogenase" |
Protein length | 271 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MSFDINWSTL ESDNRLNDLI RKHLNSYLQN TQLPSYVSNL RVLDFDLGKV
GPAITLKEIT DPLDEFYDSI REEADQETEE NNDNKEDSEH ICPDRTIANH
EGPKDDFEAP VVMPSPNDIQ FLLEVEYKGD LLVTIGADLV LNYPVEKFMT
LPVKLSISDI GLHSLCIVAC LSKQLFLSFL CDVSDPALDD NQTVLDPKGP
ILAATKPLER ISIVRSMKIE TEIGEQYQGQ GSVLRSVGEL EQFLFTIFKD
FLRKELAWPS WINLDFNDGD E
GPAITLKEIT DPLDEFYDSI REEADQETEE NNDNKEDSEH ICPDRTIANH
EGPKDDFEAP VVMPSPNDIQ FLLEVEYKGD LLVTIGADLV LNYPVEKFMT
LPVKLSISDI GLHSLCIVAC LSKQLFLSFL CDVSDPALDD NQTVLDPKGP
ILAATKPLER ISIVRSMKIE TEIGEQYQGQ GSVLRSVGEL EQFLFTIFKD
FLRKELAWPS WINLDFNDGD E
Legend
- X Phoshorylation
- X Ubiquitination
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[12, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[49, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[78, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[78, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[85, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[88, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[88, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[198, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[206, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |