Giltae Song, Luoxin Zhang, Tomas Vinar, Webb Miller. CAGE: Combinatorial Analysis of Gene-Cluster Evolution. Journal of Computational Biology, 17(9):1227-1232. 2010. Early version appeared in RECOMB-CG 2009.
Download preprint: not available
Download from publisher: http://dx.doi.org/10.1089/cmb.2010.0094
Related web page: not available
Bibliography entry: BibTeX
See also: early version
Abstract:
Much important evolutionary activity occurs in gene clusters, where a copy of a gene may be free to acquire new functions. Current computational methods to extract evolutionary information from sequence data for such clusters are suboptimal, in part because accurate sequence data are often lacking in these genomic regions, making existing methods difficult to apply. We describe a new method for reconstructing the recent evolutionary history of gene clusters, and evaluate its performance on both simulated data and actual human gene clusters.
Last modified: 09.01.2011
Contact: Tomáš Vinař, KAI FMFI UK, Mlynská Dolina, 84248 Bratislava, Slovakia
Broňa Brejová, KI FMFI UK, Mlynská Dolina, 84248 Bratislava, Slovakia
Office: M-163 Phone: +421(2)60295207
E-mail: 