Petra Kubincová. Mapping between Genomes. Bachelor thesis, Comenius University in Bratislava, 2014. Supervised by Broňa Brejová.
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Abstract:
In this thesis we focus on the problem of mapping regions between genomes. The goal is to desing and implement a practical tool for efficiently mapping genomic regions from one genome to another, based on genomic alignments computed by existing programs. We propose representation of the alignment data and file formats allowing efficient data access, and discuss theoretical problems related to mapping. We also describe similar existing tools and compare them with our tool.