Basic Information
Name | Hexaprenyl pyrophosphate synthase, mitochondrial (HPS) (EC 2.5.1.-) |
Uniprot ID | P18900 |
Systematic gene name | YBR003W |
Standard gene name | COQ1 |
Gene names | COQ1 YBR003W YBR0109 |
Description from SGD | YBR003W COQ1 SGDID:S000000207, Chr II from 242809-244230, Genome Release 64-3-1, Verified ORF, "Hexaprenyl pyrophosphate synthetase; catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis" |
Protein length | 473 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MFQRSGAAHH IKLISSRRCR FKSSFAVALN AASKLVTPKI LWNNPISLVS
KEMNTLAKNI VALIGSGHPV LNKVTSYYFE TEGKKVRPLL VLLLSRALSE
IPMTERNHLK IDKSDVPEDP IYSKPSQNQL FQRPASSISP LHILHGIKPL
NPLTKGPEPL PEETFDKQRG ILPKQRRLAE IVEMIHTASL LHDDVIDHSD
TRRGRPSGNA AFTNKMAVLA GDFLLGRATV SISRLHNPEV VELMSNSIAN
LVEGEFMQLK NTSIDADIDT IENGHKLLPV PSKKLEVKEH DFRVPSRQQG
LQLSHDQIIE TAFEYYIHKT YLKTAALISK SCRCAAILSG ASPAVIDECY
DFGRNLGICF QLVDDMLDFT VSGKDLGKPS GADLKLGIAT APVLFAWKED
PSLGPLISRN FSERGDVEKT IDSVRLHNGI AKTKILAEEY RDKALQNLRD
SLPESDARSA LEFLTNSILT RRK
KEMNTLAKNI VALIGSGHPV LNKVTSYYFE TEGKKVRPLL VLLLSRALSE
IPMTERNHLK IDKSDVPEDP IYSKPSQNQL FQRPASSISP LHILHGIKPL
NPLTKGPEPL PEETFDKQRG ILPKQRRLAE IVEMIHTASL LHDDVIDHSD
TRRGRPSGNA AFTNKMAVLA GDFLLGRATV SISRLHNPEV VELMSNSIAN
LVEGEFMQLK NTSIDADIDT IENGHKLLPV PSKKLEVKEH DFRVPSRQQG
LQLSHDQIIE TAFEYYIHKT YLKTAALISK SCRCAAILSG ASPAVIDECY
DFGRNLGICF QLVDDMLDFT VSGKDLGKPS GADLKLGIAT APVLFAWKED
PSLGPLISRN FSERGDVEKT IDSVRLHNGI AKTKILAEEY RDKALQNLRD
SLPESDARSA LEFLTNSILT RRK
Legend
- X Phoshorylation
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
Use imported representation
Loading structure from server... It may take a while.
If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.
- Internet Explorer: sorry. IE doesn't support WebGL.
- Firefox (version 4 or later): try force enable WebGL.
- Chrome: try force enable WebGL.
- Safari: enable WebGL.
References
[23, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[23, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[167, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[263, Phos] | Vlastaridis P, Kyriakidou P, Chaliotis A, et al (2017) Estimating the total number of phosphoproteins and phosphorylation sites in eukaryotic proteomes. GigaScience 6:1–11. (Publication) (All modifications) |
[263, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[263, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[434, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |