Yip, J., Wang, S., Tan, J., Lim, T.K., Lin, Q., Yu, Z., Karmon, O., Pines, O., Lehming, N. (2021). Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation. iScience 24: 103354.
https://doi.org/10.1016/j.isci.2021.103354

PTMs of cysteine desulfurase Nfs1 in response to DNA damage

Uniprot ID Systematic gene name Standard gene name Position Modification type
P25374 YCL017C NFS1 128 Deamidation
P25374 YCL017C NFS1 132 Deamidation
P25374 YCL017C NFS1 244 Methionine oxidation
P25374 YCL017C NFS1 244 Deamidation
P25374 YCL017C NFS1 286 Deamidation
P25374 YCL017C NFS1 289 Deamidation
P25374 YCL017C NFS1 328 Deamidation