Wang, S., Ramamurthy, D., Tan, J., Liu, J., Yip, J., Chua, A., Yu, Z., Lim, T.K., Lin, Q., Pines, O., Lehming, N. (2020). Post-translational modifications of fumarase regulate its enzyme activity and function in respiration and the DNA damage response. J Mol Biol 432: 6108-6126.
https://doi.org/10.1016/j.jmb.2020.09.021
Succinylation, ubiquitination, phosphorylation and deamidation of fumarase Fum1 affected by respiration and DNA damage response
| Uniprot ID | Systematic gene name | Standard gene name | Position | Modification type |
|---|---|---|---|---|
| P08417 | YPL262W | FUM1 | 78 | K-Succinylation |
| P08417 | YPL262W | FUM1 | 78 | Ubiquitination |
| P08417 | YPL262W | FUM1 | 79 | K-Succinylation |
| P08417 | YPL262W | FUM1 | 79 | Ubiquitination |
| P08417 | YPL262W | FUM1 | 96 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 122 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 124 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 126 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 128 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 239 | Deamidation |
| P08417 | YPL262W | FUM1 | 245 | K-Succinylation |
| P08417 | YPL262W | FUM1 | 264 | K-Succinylation |
| P08417 | YPL262W | FUM1 | 285 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 303 | Phoshorylation |
| P08417 | YPL262W | FUM1 | 429 | K-Succinylation |